Cytoskeletal alterations in neuronal cells implicate Toxoplasma gondii secretory machinery and host microRNA-containing extracellular vesicles

Abstract The widespread protozoan Toxoplasma gondii chronically infects neural tissue in vertebrates and is linked to various neurological and neuropsychiatric disorders in humans. However, its effects on sparsely infected neurons and on broader neural circuits remain elusive. Our study reveals that...

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Hlavní autoři:	Thomas Mazza, Morteza Aslanzadeh, Lïse Berentsen, Franziska Bonath, Marc R. Friedländer, Antonio Barragan
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2025-04-01
Edice:	Scientific Reports
Témata:	Neuron Extracellular vesicle microRNA Host–pathogen interaction Apicomplexan parasites Cytoskeleton
On-line přístup:	https://doi.org/10.1038/s41598-025-96298-8
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