Cytoskeletal alterations in neuronal cells implicate Toxoplasma gondii secretory machinery and host microRNA-containing extracellular vesicles

Abstract The widespread protozoan Toxoplasma gondii chronically infects neural tissue in vertebrates and is linked to various neurological and neuropsychiatric disorders in humans. However, its effects on sparsely infected neurons and on broader neural circuits remain elusive. Our study reveals that...

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Главные авторы:	Thomas Mazza, Morteza Aslanzadeh, Lïse Berentsen, Franziska Bonath, Marc R. Friedländer, Antonio Barragan
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Nature Portfolio 2025-04-01
Серии:	Scientific Reports
Предметы:	Neuron Extracellular vesicle microRNA Host–pathogen interaction Apicomplexan parasites Cytoskeleton
Online-ссылка:	https://doi.org/10.1038/s41598-025-96298-8
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