A functional overlap between actively transcribed genes and chromatin insulator elements

Abstract The mammalian genome is organised into large topologically associating domains (TADs) and smaller sub-TADs or enhancer-promoter loops, which may contribute to the regulation of gene expression. These dynamic structures arise, at least partly, via cohesin-mediated loop extrusion delimited by...

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Үндсэн зохиолчид:	Lucy J Cornell, Caroline L Harrold, Susannah Holliman, Felice Tsang, Matthew E Gosden, Lars L P Hanssen, Rosa Stolper, Damien J Downes, Daniel Biggs, Chris Preece, Samy Alghadban, Jacqueline A Sharpe, Benjamin Davies, Jacqueline A Sloane-Stanley, Jim R Hughes, Douglas R Higgs, Mira T Kassouf
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Springer Nature 2026-03-01
Цуврал:	The EMBO Journal
Нөхцлүүд:	CTCF Domains Insulators Regulation Transcription
Онлайн хандалт:	https://doi.org/10.1038/s44318-026-00730-2
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!