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Novel human pluripotent stem cell-derived hypothalamus organoids demonstrate cellular diversity

Summary: The hypothalamus is a region of the brain that plays an important role in regulating body functions and behaviors. There is a growing interest in human pluripotent stem cells (hPSCs) for modeling diseases that affect the hypothalamus. Here, we established an hPSC-derived hypothalamus organo...

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Bibliografische Detailangaben
Hauptverfasser: Lily Sarrafha, Drew R. Neavin, Gustavo M. Parfitt, Ilya A. Kruglikov, Kristen Whitney, Ricardo Reyes, Elena Coccia, Tatyana Kareva, Camille Goldman, Regine Tipon, Gist Croft, John F. Crary, Joseph E. Powell, Joel Blanchard, Tim Ahfeldt
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2023-09-01
Schriftenreihe:iScience
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Online-Zugang:http://www.sciencedirect.com/science/article/pii/S2589004223016024
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