EPO receptor gain-of-function causes hereditary polycythemia, alters CD34 cell differentiation and increases circulating endothelial precursors.

<h4>Background</h4>Gain-of-function of erythropoietin receptor (EPOR) mutations represent the major cause of primary hereditary polycythemia. EPOR is also found in non-erythroid tissues, although its physiological role is still undefined.<h4>Methodology/principal findings</h4>We describe a family wi...

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Autors principals:	Silverio Perrotta, Valeria Cucciolla, Marcella Ferraro, Luisa Ronzoni, Annunziata Tramontano, Francesca Rossi, Anna Chiara Scudieri, Adriana Borriello, Domenico Roberti, Bruno Nobili, Maria Domenica Cappellini, Adriana Oliva, Giovanni Amendola, Anna Rita Migliaccio, Patrizia Mancuso, Ines Martin-Padura, Francesco Bertolini, Donghoon Yoon, Josef T Prchal, Fulvio Della Ragione
Format:	Artigo
Idioma:	Inglês
Publicat:	Public Library of Science (PLoS) 2010-08-01
Col·lecció:	PLoS ONE
Accés en línia:	https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20700488/?tool=EBI
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