Assessment of fragile histidine triad (FHIT) gene expression as a predictive biomarker of therapeutic response in chronic myeloid leukemia

BACKGROUND: The accumulation of other abnormalities in both genetic and epigenetic pathways, in addition to the BCR-ABL1 oncoprotein, affects the overall clinical consequences of chronic myeloid leukemia (CML), including treatment responsiveness. OBJECTIVES: This study investigated the expression le...

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Главные авторы:	Noor Hashim Ismail, Amal Mohamed Ali, Asmaa Amer Almukhtar
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Wolters Kluwer Medknow Publications 2026-01-01
Серии:	Iraqi Journal of Hematology
Предметы:	chronic myeloid leukemia fragile histidine triad gene expression imatinib mesylate treatment response
Online-ссылка:	https://journals.lww.com/10.4103/ijh.ijh_140_25
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