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Assessment of fragile histidine triad (FHIT) gene expression as a predictive biomarker of therapeutic response in chronic myeloid leukemia

BACKGROUND: The accumulation of other abnormalities in both genetic and epigenetic pathways, in addition to the BCR-ABL1 oncoprotein, affects the overall clinical consequences of chronic myeloid leukemia (CML), including treatment responsiveness. OBJECTIVES: This study investigated the expression le...

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Principais autores: Noor Hashim Ismail, Amal Mohamed Ali, Asmaa Amer Almukhtar
Format: Artigo
Sprog:Inglês
Udgivet: Wolters Kluwer Medknow Publications 2026-01-01
Serier:Iraqi Journal of Hematology
Fag:
chronic myeloid leukemia
fragile histidine triad gene expression
imatinib mesylate
treatment response
Online adgang:https://journals.lww.com/10.4103/ijh.ijh_140_25
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