Development and validation of a nomogram based on tumor margin irregularity and alpha-fetoprotein for predicting microvascular invasion in hepatocellular carcinoma

ObjectiveTo develop and externally validate a preoperative nomogram based on tumor margin irregularity and alpha-fetoprotein (AFP) positivity for predicting microvascular invasion (MVI) in hepatocellular carcinoma (HCC).MethodsThis retrospective multicenter study included a training cohort of 487 pa...

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Detalhes bibliográficos

Principais autores:	Xiang Huang, Xiaofeng Chen, Xiangguang Chen, Ruibin Huang, Zhuozhi Dai, Ruyao Zhuang, Zhiqi Yang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2026-06-01
coleção:	Frontiers in Oncology
Assuntos:	alpha-fetoprotein computed tomography hepatocellular carcinoma microvascular invasion nomogram
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fonc.2026.1821034/full
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