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Development and validation of a nomogram based on tumor margin irregularity and alpha-fetoprotein for predicting microvascular invasion in hepatocellular carcinoma

ObjectiveTo develop and externally validate a preoperative nomogram based on tumor margin irregularity and alpha-fetoprotein (AFP) positivity for predicting microvascular invasion (MVI) in hepatocellular carcinoma (HCC).MethodsThis retrospective multicenter study included a training cohort of 487 pa...

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Principais autores: Xiang Huang, Xiaofeng Chen, Xiangguang Chen, Ruibin Huang, Zhuozhi Dai, Ruyao Zhuang, Zhiqi Yang
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2026-06-01
Serier:Frontiers in Oncology
Fag:
alpha-fetoprotein
computed tomography
hepatocellular carcinoma
microvascular invasion
nomogram
Online adgang:https://www.frontiersin.org/articles/10.3389/fonc.2026.1821034/full
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