Autoantibodies neutralizing type I IFNs in 40% of patients with WNV encephalitis in seven new cohortsAnti–type I IFN auto-Abs in WNV encephalitis

In 13 cohorts of individuals with WNV infection, the risk of WNV encephalitis is increased 20 to >>2,000 times by circulating auto-Abs neutralizing type I IFNs, depending on the concentration and combination of type I IFNs neutralized and patient age.

Bibliografski detalji

Glavni autori:	Adrian Gervais, Francesca Trespidi, Alessandro Ferrari, Francesca Rovida, Astrid Marchal, Stefania Croce, Irene Cassaniti, Mattia Moratti, Jennifer L. Uhrlaub, David M. Florian, Karin Stiasny, Elisa Burdino, Micol Angelini, Lucy Bizien, Daniele Lilleri, Veronica Codullo, Tal Freund, Yael Paran, Avi Gadoth, Roni Biran, Alessandro Mancon, Camilla Lucca, Stefania Vogiatzis, Monia Pacenti, Mélodie Aubart, Marco Zecca, Patrizia Comoli, Maria Antonietta Avanzini, Jacques Fellay, Antonio Piralla, Francesca Conti, Alberto Dolci, Luisa Barzon, Valeria Ghisetti, Tiziana Lazzarotto, Danilo Cereda, Alessandro Aiuti, Emmanuelle Jouanguy, Paul Bastard, Margaret R. MacDonald, Charles M. Rice, Anne Puel, Laurent Abel, Giada Rossini, Davide Mileto, Yannick Simonin, Anna Nagy, David Hagin, Kristy O. Murray, Fausto Baldanti, Judith H. Aberle, Aurélie Cobat, Shen-Ying Zhang, Jean-Laurent Casanova, Alessandro Borghesi
Format:	Artigo
Jezik:	Inglês
Izdano:	Rockefeller University Press 2026-03-01
Serija:	Journal of Human Immunity
Online pristup:	https://rupress.org/jhi/article-pdf/doi/10.70962/jhi.20250189/2028254/jhi_20250189.pdf
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