Auto-antibodies neutralizing type I interferons in ~10% of Moroccan patients with life-threatening COVID-19

IntroductionAutoantibodies neutralizing type I interferon (AAN-I-IFN) have been found in at least 10-15% of critical COVID-19 pneumonia cases in various studies across North and Latin America, Oceania, Europe, and Asia. We sought to analyze the prevalence of AAN-I-IFN and describe the demographic, c...

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Autors principals:	Halima Kholaiq, Adrian Gervais, Paul Bastard, Hind Ouair, Lucy Bizien, Amyrath Géraldo, Fatima Ailal, Ibtihal Benhsaien, Assiya El Kettani, Ouissal Aissaoui, Naima Amenzoui, Chafik El Kettani El Hamidi, Boubaker Charra, Maha Soussi Abdallaoui, Rachid Al Harrar, Lahoucine Barrou, Mohamed Benghanem Gharbi, Moulay Hicham Afif, Qian Zhang, Laurent Abel, Aurélie Cobat, Anne Puel, Emmanuelle Jouanguy, Jean-Laurent Casanova, Ahmed Aziz Bousfiha, Jalila El Bakkouri
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2026-07-01
Col·lecció:	Frontiers in Immunology
Matèries:	autoantibodies COVID-19 inborn errors of immunity SARS-CoV-2 type-I interferons viral infection
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1870598/full
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