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An optimized protocol for the generation of HBV viral antigen-specific T lymphocytes from pluripotent stem cells

Summary: In T cell-based cancer immunotherapy, tumor antigen (Ag)-specific CD8+ cytotoxic T lymphocytes (CTLs) can specifically target tumor Ags on malignant cells. This promising approach drove us to adopt this strategy of T cell transfer (ACT)-based immunotherapy for chronic viral infections. Here...

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Principais autores: Mohammad Haque, Xiaofang Xiong, Fengyang Lei, Jugal Kishore Das, Jianxun Song
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2021-03-01
Serija:STAR Protocols
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Online dostop:http://www.sciencedirect.com/science/article/pii/S2666166720302513
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