Metabolic fitness of NAC1-deficient Tregs in the tumor microenvironment fuels tumor growth
The nucleus accumbens-associated protein 1 (NAC1) has recently emerged as a pivotal factor in oncogenesis by promoting glycolysis. Deletion of NAC1 in regulatory T cells (Tregs) has been shown to enhance FoxP3 stability, a suppressor of glycolysis. This study delves into the intriguing dual role of...
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| Principais autores: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical investigation
2025-02-01
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| Serier: | JCI Insight |
| Fag: | |
| Online adgang: | https://doi.org/10.1172/jci.insight.186000 |
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