Access to PCNA by Srs2 and Elg1 Controls the Choice between Alternative Repair Pathways in <named-content content-type="genus-species">Saccharomyces cerevisiae</named-content>

ABSTRACT During DNA replication, stalling can occur when the replicative DNA polymerases encounter lesions or hard-to replicate regions. Under these circumstances, the processivity factor PCNA gets ubiquitylated at lysine 164, inducing the DNA damage tolerance (DDT) mechanisms that can bypass lesion...

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Hlavní autoři:	Matan Arbel, Alex Bronstein, Soumitra Sau, Batia Liefshitz, Martin Kupiec
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology 2020-06-01
Edice:	mBio
Témata:	DNA repair Elg1 Rad52 salvage pathway Srs2 homologous recombination
On-line přístup:	https://journals.asm.org/doi/10.1128/mBio.00705-20
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