Panax Notoginseng Saponins Protect Cardiac Myocytes Against Endoplasmic Reticulum Stress and Associated Apoptosis Through Mediation of Intracellular Calcium Homeostasis

Endoplasmic reticulum (ER) stress has been demonstrated to play important roles in the pathogenesis of various cardiovascular diseases. The ER stress pathway is therefore a promising therapeutic target in cardiovascular disease. Although Panax notoginseng saponins (PNS) are one of the patent medicin...

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Bibliografische Detailangaben

Hauptverfasser:	Jun Chen, Rui Xue, Li Li, Li Li Xiao, Jiahong Shangguan, Wenjing Zhang, Xueyang Bai, Gangqiong Liu, Ling Li
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2019-09-01
Schriftenreihe:	Frontiers in Pharmacology
Schlagworte:	Panax notoginseng saponins endoplasmic reticulum stress apoptosis intracellular calcium homeostasis ryanodine receptor
Online-Zugang:	https://www.frontiersin.org/article/10.3389/fphar.2019.01013/full
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