Panax Notoginseng Saponins Protect Cardiac Myocytes Against Endoplasmic Reticulum Stress and Associated Apoptosis Through Mediation of Intracellular Calcium Homeostasis

Endoplasmic reticulum (ER) stress has been demonstrated to play important roles in the pathogenesis of various cardiovascular diseases. The ER stress pathway is therefore a promising therapeutic target in cardiovascular disease. Although Panax notoginseng saponins (PNS) are one of the patent medicin...

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Detalhes bibliográficos

Principais autores:	Jun Chen, Rui Xue, Li Li, Li Li Xiao, Jiahong Shangguan, Wenjing Zhang, Xueyang Bai, Gangqiong Liu, Ling Li
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2019-09-01
coleção:	Frontiers in Pharmacology
Assuntos:	Panax notoginseng saponins endoplasmic reticulum stress apoptosis intracellular calcium homeostasis ryanodine receptor
Acesso em linha:	https://www.frontiersin.org/article/10.3389/fphar.2019.01013/full
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