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Dysfunctional tetraspanin 7 (TSP‐7) in Caenorhabditis elegans promotes; increases in average life‐ & health‐span, stress‐induced survival and motility

Caenorhabditis elegans (C. elegans) tetraspanin‐7 (TSP‐7) protein is an orthologue of the Human tetraspanin CD63, which has recently been shown to be a negative regulator of autophagy. In this study a mutant strain of wild‐type (WT) C. elegans (tm5761) with a 352 bp deletion in the tsp‐7 gene, was s...

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Principais autores: Brogan Jones, Laurence Seabra, Francesco Michelangeli
פורמט: Artigo
שפה:Inglês
יצא לאור: Wiley 2025-06-01
סדרה:FEBS Open Bio
נושאים:
autophagy
C. elegans
health‐span
life‐span
tetraspanin
גישה מקוונת:https://doi.org/10.1002/2211-5463.70013
תגים: הוספת תג
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