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Intercalation of small molecules into DNA in chromatin is primarily controlled by superhelical constraint.

The restricted access of regulatory factors to their binding sites on DNA wrapped around the nucleosomes is generally interpreted in terms of molecular shielding exerted by nucleosomal structure and internucleosomal interactions. Binding of proteins to DNA often includes intercalation of hydrophobic...

詳細記述

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書誌詳細
主要な著者: Rosevalentine Bosire, Péter Nánási, László Imre, Beatrix Dienes, Árpád Szöőr, Anett Mázló, Attila Kovács, Ralf Seidel, György Vámosi, Gábor Szabó
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science (PLoS) 2019-01-01
シリーズ:PLoS ONE
オンライン・アクセス:https://doi.org/10.1371/journal.pone.0224936
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