Intercalation of small molecules into DNA in chromatin is primarily controlled by superhelical constraint.
The restricted access of regulatory factors to their binding sites on DNA wrapped around the nucleosomes is generally interpreted in terms of molecular shielding exerted by nucleosomal structure and internucleosomal interactions. Binding of proteins to DNA often includes intercalation of hydrophobic...
שמור ב:
| Principais autores: | , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Public Library of Science (PLoS)
2019-01-01
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| סדרה: | PLoS ONE |
| גישה מקוונת: | https://doi.org/10.1371/journal.pone.0224936 |
| תגים: |
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