Histone demethylase KDM9 activates the CCND1/AKT pathway to promote the malignant progression of gliomas through interaction with BRD2
Abstract Gliomas are highly aggressive brain tumors with limited treatment options, thus, it is necessary to identify new molecular targets for therapeutic intervention. Epigenetic aberration plays a vital role in the malignant progression of tumors. KDM9 is a histone demethylase, but its function a...
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| Principais autores: | , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Springer
2025-11-01
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| Serija: | Cellular and Molecular Life Sciences |
| Teme: | |
| Online dostop: | https://doi.org/10.1007/s00018-025-05900-9 |
| Oznake: |
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