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The IrlS2-IrlR2 two-component system is a global regulator of biofilm formation, stress adaptation, and virulence in Burkholderia pseudomallei

ABSTRACT Burkholderia pseudomallei, which causes melioidosis, is an adaptable pathogen that survives in diverse environments. Two-component systems (TCSs) play pivotal roles in bacterial signal transduction and adaptation, yet the functions of most TCSs in B. pseudomallei remain poorly characterized...

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Kaydedildi:
Asıl Yazarlar: Fang Chen, Jian Luo, Yingjuan Wang, Shen Tian, Xun Kang, Nan Zhang, Wan Zheng, Wenting Li, Qianfeng Xia, Dai Kuang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2026-03-01
Seri Bilgileri:mSphere
Konular:
Burkholderia pseudomallei
two-component systems
biofilm formation
stress adaptation
virulence regulation
Online Erişim:https://journals.asm.org/doi/10.1128/msphere.00744-25
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