The IrlS2-IrlR2 two-component system is a global regulator of biofilm formation, stress adaptation, and virulence in Burkholderia pseudomallei

ABSTRACT Burkholderia pseudomallei, which causes melioidosis, is an adaptable pathogen that survives in diverse environments. Two-component systems (TCSs) play pivotal roles in bacterial signal transduction and adaptation, yet the functions of most TCSs in B. pseudomallei remain poorly characterized...

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Bibliografische Detailangaben

Hauptverfasser:	Fang Chen, Jian Luo, Yingjuan Wang, Shen Tian, Xun Kang, Nan Zhang, Wan Zheng, Wenting Li, Qianfeng Xia, Dai Kuang
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology 2026-03-01
Schriftenreihe:	mSphere
Schlagworte:	Burkholderia pseudomallei two-component systems biofilm formation stress adaptation virulence regulation
Online-Zugang:	https://journals.asm.org/doi/10.1128/msphere.00744-25
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