Is Desmin Propensity to Aggregate Part of its Protective Function?
Desmin is the major protein component of the intermediate filaments (IFs) cytoskeleton in muscle cells, including cardiac. The accumulation of cleaved and misfolded desmin is a cellular hallmark of heart failure (HF). These desmin alterations are reversed by therapy, suggesting a causal role for the...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
MDPI AG
2020-02-01
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| Collection: | Cells |
| Sujets: | |
| Accès en ligne: | https://www.mdpi.com/2073-4409/9/2/491 |
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