The Role of T Lymphocytes in the Pathogenesis of Paroxysmal Nocturnal Hemoglobinuria

Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired hematopoietic stem cell genetic mutation disease that causes defective erythrocyte membrane hemolysis. Its pathologic basis is the mutation of the PIG-A gene, whose product is necessary for the synthesis of glycosylphosphatidylinositol (GPI) a...

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Hlavní autoři:	Chenyuan Li, Xifeng Dong, Huaquan Wang, Zonghong Shao
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2021-12-01
Edice:	Frontiers in Immunology
Témata:	paroxysmal nocturnal hemoglobinuria aplastic anemia T lymphocytes pathogenesis immune escape
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.777649/full
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