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The Role of T Lymphocytes in the Pathogenesis of Paroxysmal Nocturnal Hemoglobinuria

Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired hematopoietic stem cell genetic mutation disease that causes defective erythrocyte membrane hemolysis. Its pathologic basis is the mutation of the PIG-A gene, whose product is necessary for the synthesis of glycosylphosphatidylinositol (GPI) a...

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Autors principals: Chenyuan Li, Xifeng Dong, Huaquan Wang, Zonghong Shao
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021-12-01
Col·lecció:Frontiers in Immunology
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Accés en línia:https://www.frontiersin.org/articles/10.3389/fimmu.2021.777649/full
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