The aptamer BC 007 for treatment of dilated cardiomyopathy: evaluation in Doberman  Pinschers of efficacy and outcomes

Abstract Aims Aptamer BC 007, a 15‐mer single‐strand DNA oligonucleotide (5'‐GGTTGGTGTGGTTGG‐3'), was developed to neutralize functional autoantibodies that bind to the extracellular domains of G protein‐coupled receptors (GPCR‐AAB), leading to the modulation of receptor‐mediated signalling cascades...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Sabine Werner, Gerd Wallukat, Niels‐Peter Becker, Katrin Wenzel, Johannes Müller, Ingolf Schimke, Gerhard Wess
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Oxford University Press 2020-06-01
Sarja:	ESC Heart Failure
Aiheet:	Anti‐beta1‐adrenergic receptor antibodies BC 007 Cardiomyopathy Doberman Pinscher Heard failure Treatment
Linkit:	https://doi.org/10.1002/ehf2.12628
Tagit:	Lisää tagi Ei tageja, Lisää ensimmäinen tagi!