Controversial efficacy of antithrombin followed by recombinant thrombomodulin administration in patients with sepsis-induced disseminated intravascular coagulation: an analysis of postmarketing surveillance data

Abstract Background Anticoagulant therapy is considered useful for sepsis patients with disseminated intravascular coagulation (DIC); however, the efficacy of combination therapy with anticoagulants is still under investigation. Methods We evaluated anticoagulant use in 1,770 patients with sepsis-in...

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Principais autores:	Yutaka Eguchi, Hiroyuki Nagafuchi, Toshiaki Ikeda
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2025-11-01
Series:	Thrombosis Journal
Assuntos:	SOFA score JAAM-defined DIC score Mortality Adverse events Propensity score-adjusted analysis
Acceso en liña:	https://doi.org/10.1186/s12959-025-00794-w
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