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Sepsis-Associated DIC with Decreased Levels of Antithrombin and Fibrinogen is the Target for Combination Therapy with Thrombomodulin Alfa and Antithrombin

Abstract Background Disseminated intravascular coagulation (DIC) is not a homogeneous condition, but rather includes heterogeneous conditions, and its pathophysiology and outcome vary considerably depending on the background. Although anticoagulant therapy is expected to be of...

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Main Authors: Hideo Wada, Kazuo Kawasugi, Goichi Honda, Noriaki Kawano, Toshimasa Uchiyama, Seiji Madoiwa, Naoki Takezako, Kei Suzuki, Yoshinobu Seki, Takayuki Ikezoe, Toshiaki Iba, Kohji Okamoto
Format: Artigo
Language:Inglês
Published: Georg Thieme Verlag KG 2023-01-01
Series:TH Open
Subjects:
thrombomodulin
antithrombin
fibrinogen
disseminated intravascular coagulation
sepsis
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/a-2009-9073
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