High expression of nuclear factor 90 (NF90) leads to mitochondrial degradation in skeletal and cardiac muscles.

While NF90 has been known to participate in transcription, translation and microRNA biogenesis, physiological functions of this protein still remain unclear. To uncover this, we generated transgenic (Tg) mice using NF90 cDNA under the control of β-actin promoter. The NF90 Tg mice exhibited a reducti...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Takuma Higuchi, Shuji Sakamoto, Yoshihiko Kakinuma, Shoko Kai, Ken-Ichi Yagyu, Hiroshi Todaka, Eunsup Chi, Shoshiro Okada, Takako Ujihara, Keiko Morisawa, Masafumi Ono, Yasunori Sugiyama, Waka Ishida, Atsuki Fukushima, Masayuki Tsuda, Yasutoshi Agata, Taketoshi Taniguchi
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Public Library of Science (PLoS) 2012-01-01
Schriftenreihe:	PLoS ONE
Online-Zugang:	http://europepmc.org/articles/PMC3422296?pdf=render
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