Quantitative proteomics defines mechanisms of antiviral defence and cell death during modified vaccinia Ankara infection

Abstract Modified vaccinia Ankara (MVA) virus does not replicate in human cells and is the vaccine deployed to curb the current outbreak of mpox. Here, we conduct a multiplexed proteomic analysis to quantify >9000 cellular and ~80% of viral proteins throughout MVA infection of human fibroblasts and...

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Detalles Bibliográficos

Principais autores:	Jonas D. Albarnaz, Joanne Kite, Marisa Oliveira, Hanqi Li, Ying Di, Maria H. Christensen, Joao A. Paulo, Robin Antrobus, Steven P. Gygi, Florian I. Schmidt, Edward L. Huttlin, Geoffrey L. Smith, Michael P. Weekes
Formato:	Artigo
Idioma:	Inglês
Publicado:	Nature Portfolio 2023-12-01
Series:	Nature Communications
Acceso en liña:	https://doi.org/10.1038/s41467-023-43299-8
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