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Viral manipulation of the HLA class I antigen processing and presentation pathway

Major histocompatibility complex (MHC, human leukocyte antigen [HLA] in humans) class I molecules present peptides at the cell surface to cytotoxic immune cells. Peptides are generated and selected for MHC class I presentation in the antigen processing and presentation (APP) pathway. Recognition of...

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Principais autores: Dominic S Nolan, Arwen F Altenburg
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2025-12-01
Serier:Frontiers in Immunology
Fag:
HLA
immune evasion
virus
infection
antigen presentation
CD8+ T cells
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1694498/full
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