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The PH domain from the Toxoplasma gondii PH-containing protein-1 (TgPH1) serves as an ectopic reporter of phosphatidylinositol 3-phosphate in mammalian cells.

Phosphoinositide (PtdInsP) lipids recruit effector proteins to membranes to mediate a variety of functions including signal transduction and membrane trafficking. Each PtdInsP binds to a specific set of effectors through characteristic protein domains such as the PH, FYVE and PX domains. Domains wit...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Krishna Chintaluri, Brady D Goulden, Camilyn Clemenza, Golam Saffi, Emily Miraglia, Gerald R V Hammond, Roberto J Botelho
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science (PLoS) 2018-01-01
Cyfres:PLoS ONE
Mynediad Ar-lein:http://europepmc.org/articles/PMC5988325?pdf=render
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