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Implication of the Mediator kinase module in CIZ1 recruitment and gene silencing by Xist during the initiation of X inactivation

In mammals, dosage compensation between the sexes is mediated by X chromosome inactivation. The long non-coding Xist RNA initiates this process. The molecular mechanism of X-linked gene silencing is beginning to be understood. We have previously reported that the cyclin-dependent kinase CDK8 is requ...

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Bibliografiset tiedot
Päätekijät: Jingyi Chen, Kevin Halter, Timothe Weitzel, Anton Wutz
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis Group 2025-12-01
Sarja:Epigenetics Reports
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Linkit:https://www.tandfonline.com/doi/10.1080/28361512.2025.2456806
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