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Structure of human cytomegalovirus virion reveals host tRNA binding to capsid-associated tegument protein pp150

Here, cryo-EM reconstructions of human cytomegalovirus (HCMV) virions reveal host tRNAs associated with the virion’s capsid-bound tegument protein, pp150. tRNA recruitment is mediated by the interactions specific for HCMV only, suggesting the explanation for the absence of such tRNA densities in rel...

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Autors principals: Yun-Tao Liu, David Strugatsky, Wei Liu, Z. Hong Zhou
Format: Artigo
Idioma:Inglês
Publicat: Nature Portfolio 2021-09-01
Col·lecció:Nature Communications
Accés en línia:https://doi.org/10.1038/s41467-021-25791-1
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