Atomic structures and deletion mutant reveal different capsid-binding patterns and functional significance of tegument protein pp150 in murine and human cytomegaloviruses with implications for therapeutic development.

Cytomegalovirus (CMV) infection causes birth defects and life-threatening complications in immunosuppressed patients. Lack of vaccine and need for more effective drugs have driven widespread ongoing therapeutic development efforts against human CMV (HCMV), mostly using murine CMV (MCMV) as the model...

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Bibliografski detalji

Glavni autori:	Wei Liu, Xinghong Dai, Jonathan Jih, Karen Chan, Phong Trang, Xuekui Yu, Rilwan Balogun, Ye Mei, Fenyong Liu, Z Hong Zhou
Format:	Artigo
Jezik:	Inglês
Izdano:	Public Library of Science (PLoS) 2019-02-01
Serija:	PLoS Pathogens
Online pristup:	https://doi.org/10.1371/journal.ppat.1007615
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