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New Thiazoline-Tetralin Derivatives and Biological Activity Evaluation

In this study, novel N′-(3-cyclohexyl/phenyl-4-(substituted phenyl)thiazole-2(3H)-ylidene)-2-[(5,6,7,8-tetrahydronaphthalen-2-yl)oxy]acetohydrazide (4a–4k) derivatives were synthesized and their anticancer potency were evaluated on human breast adenocarcinoma cell line (MCF-7), human lung carcinoma...

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Principais autores: Gülhan Turan-Zitouni, Leyla Yurttaş, Aouatef Tabbi, Gülşen Akalın Çiftçi, Halide Edip Temel, Zafer Asım Kaplancıklı
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2018-01-01
coleção:Molecules
Assuntos:
thiazoline
tetralin (tetrahydronaftalene)
cytotoxicity
DNA synthesis inhibition
apoptosis
anticholinesterase activity
Acesso em linha:http://www.mdpi.com/1420-3049/23/1/135
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