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Molecular docking, chemo-informatic properties, alpha-amylase, and lipase inhibition studies of benzodioxol derivatives

Abstract Currently, available therapies for diabetes could not achieve normal sugar values in a high percentage of treated patients. In this research project, a series of 17 benzodioxole derivatives were evaluated as antidiabetic agents; that belong to three different groups were evaluated against l...

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Principais autores: Mohammed Hawash, Nidal Jaradat, Suhaib Shekfeh, Murad Abualhasan, Ahmad M. Eid, Linda Issa
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2021-06-01
Serier:BMC Chemistry
Fag:
Benzodioxole
α-Amylase
Lipase
Acarbose
Bioactivity
Molecular docking
Online adgang:https://doi.org/10.1186/s13065-021-00766-x
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