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NK Cell Function Regulation by TGF-β-Induced Epigenetic Mechanisms

TGF-β is a potent immunosuppressive cytokine that severely affects the function of NK cells. Tumor cells can take advantage of this ability, enriching their surrounding microenvironment with TGF-β. TGF-β can alter the expression of effector molecules and of activating and chemokine receptors, influe...

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Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Stefano Regis, Alessandra Dondero, Fabio Caliendo, Cristina Bottino, Roberta Castriconi
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Frontiers Media S.A. 2020-02-01
Sraith:Frontiers in Immunology
Ábhair:
Rochtain ar líne:https://www.frontiersin.org/article/10.3389/fimmu.2020.00311/full
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