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An exploratory metabolomic comparison of participants with fast or absent functional progression from 2CARE, a randomized, double-blind clinical trial in Huntington’s disease

Abstract Huntington’s disease (HD) is increasingly recognized for diverse pathology outside of the nervous system. To describe the biology of HD in relation to functional progression, we previously analyzed the plasma and CSF metabolome in a cross-sectional study of participants who had various degr...

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Autors principals: Andrew McGarry, Krystal Hunter, John Gaughan, Peggy Auinger, Thomas N. Ferraro, Basant Pradhan, Luigi Ferrucci, Josephine M. Egan, Ruin Moaddel
Format: Artigo
Idioma:Inglês
Publicat: Nature Portfolio 2024-01-01
Col·lecció:Scientific Reports
Accés en línia:https://doi.org/10.1038/s41598-023-50553-y
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