Distinct genetic architecture of coronary heart disease in dyslipidemia patients

Abstract Background Mutations of LDLR, APOB and PCSK9 have been well-established to cause hypercholesterolemia while the pathogenic effects of LPL has been confirmed by cohorts and functional studies in hypertriglyceridemia. However, these mutations do not fully account for all dyslipidemia, and it...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Man Huang, Xiuli Song, Shuni Zhou, Haiyan Zhang, Lijuan He, Yanghui Chen, Guangzhi Chen, Hu Ding, Jiangang Jiang, Yan Wang, Dao Wen Wang, Yang Sun, Hong Wang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2026-05-01
Edice:	BMC Medical Genomics
Témata:	Hypercholesterolemia Hypertriglyceridemia Whole exome sequencing Coronary heart disease LDLR APOB
On-line přístup:	https://doi.org/10.1186/s12920-026-02388-5
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!