GABAergic disinhibition from the BNST to PNOCARC neurons promotes HFD-induced hyperphagia

Summary: Activation of prepronociceptin (PNOC)-expressing neurons in the arcuate nucleus (ARC) promotes high-fat-diet (HFD)-induced hyperphagia. In turn, PNOCARC neurons can inhibit the anorexic response of proopiomelanocortin (POMC) neurons. Here, we validate the necessity of PNOCARC activity for H...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Tamara Sotelo-Hitschfeld, Marielle Minère, Paul Klemm, Diba Borgmann, Daria Wnuk-Lipinski, Alexander Jais, Xianglian Jia, Svenja Corneliussen, Peter Kloppenburg, Henning Fenselau, Jens Claus Brüning
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2024-06-01
Schriftenreihe:	Cell Reports
Schlagworte:	CP: Neuroscience CP: Metabolism
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S2211124724006715
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!