Why the HIV Reservoir Never Runs Dry: Clonal Expansion and the Characteristics of HIV-Infected Cells Challenge Strategies to Cure and Control HIV Infection

Antiretroviral therapy (ART) effectively reduces cycles of viral replication but does not target proviral populations in cells that persist for prolonged periods and that can undergo clonal expansion. Consequently, chronic human immunodeficiency virus (HIV) infection is sustained during ART by a res...

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Päätekijät:	Chuen-Yen Lau, Matthew A. Adan, Frank Maldarelli
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	MDPI AG 2021-12-01
Sarja:	Viruses
Aiheet:	HIV clonal expansion reservoir persistence cure
Linkit:	https://www.mdpi.com/1999-4915/13/12/2512
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