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Why the HIV Reservoir Never Runs Dry: Clonal Expansion and the Characteristics of HIV-Infected Cells Challenge Strategies to Cure and Control HIV Infection

Antiretroviral therapy (ART) effectively reduces cycles of viral replication but does not target proviral populations in cells that persist for prolonged periods and that can undergo clonal expansion. Consequently, chronic human immunodeficiency virus (HIV) infection is sustained during ART by a res...

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Autori principali: Chuen-Yen Lau, Matthew A. Adan, Frank Maldarelli
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2021-12-01
Serie:Viruses
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Accesso online:https://www.mdpi.com/1999-4915/13/12/2512
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