Whole genome sequencing of Mycobacterium tuberculosis isolates and clinical outcomes of patients treated for multidrug-resistant tuberculosis in Tanzania

Abstract Background Tuberculosis (TB), particularly multi- and or extensive drug resistant TB, is still a global medical emergency. Whole genome sequencing (WGS) is a current alternative to the WHO-approved probe-based methods for TB diagnosis and detection of drug resistance, genetic diversity and...

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Autori principali:	Bugwesa Z. Katale, Peter M. Mbelele, Nsiande A. Lema, Susana Campino, Stephen E. Mshana, Mark M. Rweyemamu, Jody E. Phelan, Julius D. Keyyu, Mtebe Majigo, Erasto V. Mbugi, Hazel M. Dockrell, Taane G. Clark, Mecky I. Matee, Stellah Mpagama
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2020-02-01
Serie:	BMC Genomics
Soggetti:	Whole genome sequence Mycobacterium tuberculosis Multidrug-resistant tuberculosis Time-to-culture-conversion Treatment-outcomes
Accesso online:	http://link.springer.com/article/10.1186/s12864-020-6577-1
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