Whole genome sequencing of Mycobacterium tuberculosis isolates and clinical outcomes of patients treated for multidrug-resistant tuberculosis in Tanzania

Abstract Background Tuberculosis (TB), particularly multi- and or extensive drug resistant TB, is still a global medical emergency. Whole genome sequencing (WGS) is a current alternative to the WHO-approved probe-based methods for TB diagnosis and detection of drug resistance, genetic diversity and...

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Bibliografische Detailangaben

Hauptverfasser:	Bugwesa Z. Katale, Peter M. Mbelele, Nsiande A. Lema, Susana Campino, Stephen E. Mshana, Mark M. Rweyemamu, Jody E. Phelan, Julius D. Keyyu, Mtebe Majigo, Erasto V. Mbugi, Hazel M. Dockrell, Taane G. Clark, Mecky I. Matee, Stellah Mpagama
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2020-02-01
Schriftenreihe:	BMC Genomics
Schlagworte:	Whole genome sequence Mycobacterium tuberculosis Multidrug-resistant tuberculosis Time-to-culture-conversion Treatment-outcomes
Online-Zugang:	http://link.springer.com/article/10.1186/s12864-020-6577-1
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