Angiotensin-Converting Enzyme 2 Inhibits Apoptosis of Pulmonary Endothelial Cells During Acute Lung Injury Through Suppressing SMAD2 Phosphorylation

Background/Aims: Angiotensin converting enzyme 2 (ACE2) has an established role in suppressing the severity of acute lung injury (ALI), especially when it was applied together with transplantation of human umbilical cord mesenchymal stem cells (uMSCs). Although the effects of ACE2 in ALI are believe...

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Autori principali:	Yong Ji, Fengying Gao, Bo Sun, Jing Hao, Zhenwei Liu
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Cell Physiol Biochem Press GmbH & Co KG 2015-04-01
Serie:	Cellular Physiology and Biochemistry
Soggetti:	SMAD7 SMAD2 Hydrolyzing angiotensin II (AngII) Angiotensin converting enzyme 2 (ACE2) Nitric oxide (NO) Acute lung injury (ALI)
Accesso online:	http://www.karger.com/Article/FullText/374025
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