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Angiotensin-Converting Enzyme 2 Inhibits Apoptosis of Pulmonary Endothelial Cells During Acute Lung Injury Through Suppressing SMAD2 Phosphorylation

Background/Aims: Angiotensin converting enzyme 2 (ACE2) has an established role in suppressing the severity of acute lung injury (ALI), especially when it was applied together with transplantation of human umbilical cord mesenchymal stem cells (uMSCs). Although the effects of ACE2 in ALI are believe...

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Principais autores: Yong Ji, Fengying Gao, Bo Sun, Jing Hao, Zhenwei Liu
Format: Artigo
Sprog:Inglês
Udgivet: Cell Physiol Biochem Press GmbH & Co KG 2015-04-01
Serier:Cellular Physiology and Biochemistry
Fag:
SMAD7
SMAD2
Hydrolyzing angiotensin II (AngII)
Angiotensin converting enzyme 2 (ACE2)
Nitric oxide (NO)
Acute lung injury (ALI)
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