Electrochemical Synthesis of New Isoxazoles and Triazoles Tethered with Thiouracil Base as Inhibitors of Histone Deacetylases in Human Breast Cancer Cells

Histone deacetylases (HDACs) are an attractive drug target for the treatment of human breast cancer (BC), and therefore, HDAC inhibitors (HDACis) are being used in preclinical and clinical studies. The need to understand the scope of the mode of action of HDACis, as well as the report of the co-crys...

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Główni autorzy:	Divakar Vishwanath, Zhang Xi, Akshay Ravish, Arunkumar Mohan, Shreeja Basappa, Niranjan Pattehalli Krishnamurthy, Santosh L. Gaonkar, Vijay Pandey, Peter E. Lobie, Basappa Basappa
Format:	Artigo
Język:	Inglês
Wydane:	MDPI AG 2023-07-01
Seria:	Molecules
Hasła przedmiotowe:	breast cancer HDAC triazole isoxazole thiouracil drug discovery
Dostęp online:	https://www.mdpi.com/1420-3049/28/13/5254
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