Simple nutrients bypass the requirement for HLH-30 in coupling lysosomal nutrient sensing to survival.
Lysosomes are ubiquitous acidified organelles that degrade intracellular and extracellular material trafficked via multiple pathways. Lysosomes also sense cellular nutrient levels to regulate target of rapamycin (TOR) kinase, a signaling enzyme that drives growth and suppresses activity of the MiT/T...
Kaydedildi:
| Asıl Yazarlar: | , , , , , , , , , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Public Library of Science (PLoS)
2019-05-01
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| Seri Bilgileri: | PLoS Biology |
| Online Erişim: | https://doi.org/10.1371/journal.pbio.3000245 |
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