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O-GlcNAcylation at the tumor–immune interface: a metabolic post-translational code driving immune evasion and therapy resistance in cancer

Protein O-GlcNAcylation has evolved from a metabolic curiosity into a master post-translational modification that enables cancer cells to translate nutrient availability into coordinated programs of proliferation, therapy resistance, and immune evasion. In this review, we argue that hyper-O-GlcNAcyl...

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Hlavní autoři: Shanshan Liu, Peng Zhan, WenJie Tian, Jinning Gu
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2026-07-01
Edice:Frontiers in Immunology
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1854952/full
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